Start Page Monographie Diabetes mellitus


Monographie Diabetes mellitus


with type 2 diabetes mellitus and hypertension without clinically evident coronary heart disease, but with other risk factors such as age ≥55 years, retinopathy, albuminuria or smoking. LIPITOR is indicated to reduce the risk of myocardial infarction in patients with clinically evident coronary heart disease.COMPOSITION AND PACKAGING section of the product monograph. Concomitant use of angiotensin receptor antagonists (ARBs), including Sandoz Olmesartan, with aliskiren-containing drugs in patients with diabetes mellitus (type 1 or type 2) or moderate to severe renal impairment (GFR 60 mL/min/1.73.in patients with diabetes mellitus (type 1 or type 2) and/or moderate to severe renal impairment (GFR 60 ml/min/1.73m2). Therefore, the use of ramipril in combination with aliskiren-containing drugs is contraindicated in these patients (see CONTRAINDICATIONS). The use of ramipril in combination with an ARB is contraindicated in patients.Dec 12, 2018 PRODUCT MONOGRAPH. ONGLYZA® ONGLYZA is indicated in patients with type 2 diabetes mellitus to improve glycemic control.Topical KINOSTAT™ ameliorates the clinical development and progression of cataracts in dogs with diabetes mellitus. Kador PF(1), Webb TR, Bras D, Ketring K, Wyman M. Author information: (1)Therapeutic Vision Inc., Omaha, NE, USA. therapeuticvision@cox.net.of type 2 diabetes mellitus. Please refer to the respective TZD product monograph, (see WARNINGS. AND PRECAUTIONS), information when the use of these .RIVA-OLANZAPINE Product Monograph Page 2 of 63 complicated by the possibility of an increased background risk of diabetes mellitus in patients with schizophrenia and the increasing incidence of diabetes mellitus in the general population. Given these confounders, the relationship between atypical antipsychotic.insulin (with or without metformin) in adult patients with type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control when diet and exercise, and therapy with premixed or long/intermediate acting insulin (with or without metformin) do not provide adequate glycemic control.



Glykämisches Profil in der Diabetes mellitus-Tabelle



women, especially those with a history of gestational diabetes mellitus, should be carefully observed while taking VISANNE. (1) Psychiatric Patients who have a history of depression should be carefully observed. VISANNE should be discontinued if clinically relevant depression occurs or if pre-existing depression is aggravated during treatment.Manifestations of Cushing’s syndrome, effects on the metabolic control of diabetes mellitus (e.g. hyperglycaemia, glucosuria) and unmasking of latent diabetes mellitus can also be produced in some patients by systemic absorption of topical corticosteroids.TRAJENTA (linagliptin) is indicated in adult patients with type 2 diabetes mellitus (T2DM) to improve glycemic control. Monotherapy In conjunction with diet and exercise in patients for whom metformin is inappropriate due to contraindications or intolerance. Combination Therapy.Type 2 diabetes mellitus: Initially, 10 units once daily. 1. Transferring from Other Insulins to Insulin Degludec Sub-Q Type 1 and Type 2 diabetes mellitus: Initiate insulin degludec at same dosage as the total daily long- or intermediate-acting insulin dosage. 1. Insulin Degludec/ Liraglutide Fixed-combination Therapy Sub-Q.MIDODRINE (midodrine hydrochloride) may be used to attenuate symptoms of chronic orthostatic hypotension due to autonomic failure in patients with Bradbury-Eggleston syndrome, Shy-Drager syndrome, diabetes mellitus disease and Parkinson’s disease. The initiation and up-titration of midodrine therapy should be undertaken under close medical.JANUVIA® is indicated as an adjunct to diet and exercise to improve glycemic control in adultswith type 2 diabetes mellitus. [See Clinical Studies (14).] 1.2 Important Limitations of Use JANUVIA should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis, as it would not be effective in these settings.Apr 11, 2019 TRESIBA® (insulin degludec injection) - Product Monograph performed for all patients with diabetes mellitus treated with TRESIBA® (see .Trulicity ® is a once-weekly injectable prescription medicine to improve blood sugar (glucose) in adults with type 2 diabetes mellitus. It should be used along with diet and exercise. Trulicity is not recommended as the first medication to treat diabetes. It has not been studied in people who have had inflammation of the pancreas (pancreatitis).

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PRODUCT MONOGRAPH. INCLUDING PATIENT MEDICATION INFORMATION PrPRALUENT® alirocumab solution for subcutaneous injection 75 mg/mL and 150 mg/mL Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor Sanofi-aventis Canada Inc. 2905 Place Louis-R-Renaud Laval, Quebec H7V0A3.In most cases, risk factors have been identified, such as pre-existing renal insufficiency, diabetes mellitus, hypovolemia, overweight, concomitant nephrotoxic medications, or over the age of 65. Respiratory Transfusion-related acute lung injury (TRALI) has been rarely reported after treatment.aggravate pre-existing diabetes mellitus and ketoacidosis. Hypokalemia and Hyperglycemia Beta-adrenergic agonist medicines may produce significant hypokalemia in some patients which has the potential to produce adverse cardiovascular effects. The decrease in serum potassium is usually transient, not requiring supplementation. ANORO ELLIPTA should.conditions, including diabetes mellitus, and whenever there is significant tissue hypoperfusion Page 6 of 31 and hypoxemia. Lactic acidosis is characterized by elevated blood lactate levels ( 5 mmol/L), decreased blood pH, electrolyte disturbances with an increased anion gap, and an increased.Victoza® is an injectable prescription medicine that may improve blood sugar in adults with type 2 diabetes. Read important safety information, including Boxed Warning.PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION aliskiren-containing drugs is contraindicated in patients with diabetes mellitus, whether Type 1 or 2, or in patients with moderate to severe renal impairment, i.e., eGFR 60 ENTRESTOTM must not be administered with aliskiren in patients with Type 2 diabetes.identified in postmarketing surveillance in patients with type 1 and type 2 diabetes mellitus receiving sodium glucose co-transporter-2 (SGLT2) inhibitors, including JARDIANCE. Fatal cases of ketoacidosis have been reported in patients taking JARDIANCE. JARDIANCE is not indicated for the treatment of patients with type 1 diabetes mellitus.Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006. Glucagon increases blood glucose levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels.
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comorbidity (e.g., controlled hypertension, type 2 diabetes mellitus, or dyslipidemia). Limitations of Use: • The effect of CONTRAVE on cardiovascular morbidity and mortality has not been established (see WARNINGS AND PRECAUTIONS, Cardiovascular, Increase in Blood Pressure and Heart Rate).ONGLYZA is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin and a sulfonylurea when dual therapy with these two agents, with diet and exercise, does not provide adequate glycemic control (see CLINICAL TRIALS).TRULICITY is indicated for the once-weekly treatment of adult patients with type 2 diabetes mellitus to improve glycemic control, in combination with: • diet and exercise in patients for whom metformin is inappropriate due to contraindication or intolerance. • metformin, when diet and exercise plus maximal tolerated dose of metformin.Among the 16,676 patients without diabetes mellitus at baseline, the incidence of new-onset diabetes mellitus during the trial was 8.1% in patients assigned to REPATHA compared with 7.7% in those assigned to placebo. Adverse Reactions in Patients with Primary Hyperlipidemia (including Heterozygous Familial Hypercholesterolemia).Jan 28, 2019 WARNINGS AND PRECAUTIONS. Serious Warnings and Precautions. Diabetic Ketoacidosis. • Clinical trial and post-market cases of diabetic .indicated for the treatment of type 2 diabetes mellitus. Please refer to the respective TZD product monograph Warnings and Precautions information when the use of these drugs in combination with any insulin, including BASAGLAR,is contemplated. To avoid transmission of disease, a cartridge or prefilled syringe shallnot.Liraglutide, sold under the brand name Victoza among others, is a medication used to treat diabetes mellitus type 2 and obesity. In diabetes it is a less preferred agent. Its effect on long term health outcomes like heart disease and life expectancy are unclear.diabetes, hypertension, abnormal lipid profile or a family history of these. Whether oral contraceptives accentuate this risk is unclear. In low risk, non-smoking women of any age, the benefits of oral contraceptive use outweigh the possible cardiovascular risks associated with low dose formulations. Consequently.
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hyperkalaemia, particularly in patients with diabetes mellitus, chronic renal failure, pre-existing metabolic acidosis, raised plasma potassium at pre-treatment, concomitant therapy with drugs that may elevate plasma potassium and long term use of INNOHEP. In patients.AVANDIA (rosiglitazone maleate) is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus for whom all other oral antidiabetic agents, in monotherapy or in combination, do not result in adequate glycemic control or are inappropriate due to contraindications or intolerance. (See WARNINGS.Apr 26, 2019 INVOKANA® is indicated as add-on combination therapy with insulin (with or without metformin) in adult patients with type 2 diabetes mellitus .Ozempic ® is indicated for the once-weekly treatment of adult patients with type 2 diabetes mellitus to improve glycemic control, in combination with:. diet and exercise in patients for whom metformin is inappropriate due to contraindication or intolerance; metformin, when diet and exercise plus maximal tolerated dose of metformin do not achieve adequate glycemic control.Jan 18, 2018 Product Monograph. Page 1 of 45. PRODUCT MONOGRAPH. Pr. ACTOS® (non-insulin dependent diabetes mellitus, NIDDM). ACTOS.• diabetes mellitus with vascular involvement YASMIN Product Monograph Page 4 of 57 • major surgery associated with an increased risk of postoperative thromboembolism • prolonged immobilization • use with the Hepatitis C virus combination drug regimen ombitasvir, paritaprevir, ritonavir.with type 2 diabetes mellitus treated with JARDIANCE and other SGLT2 inhibitors. Some cases of DKA have been fatal. In a number of reported cases, the presentation of the condition was atypical with only moderately increased blood glucose values, below 13.9 mmol/L (250 mg/dL).Mar 5, 2019 TRULICITY® Product Monograph. Page 1 of Type 1 diabetes mellitus (formerly known as insulin-dependent diabetes mellitus or IDDM).
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diabetes mellitus, but not with other types pancreatic impairment. Immune Local Allergic Reaction As with any insulin therapy, injection site reactions may occur and include pain, redness, itching, hives, swelling, bruising and inflammation. Continuous rotation of the injection site within a given.Diabetes: The effects of Plan B® on carbohydrate metabolism are unknown. Some users of progestin-only oral contraceptives experience slight deterioration in glucose tolerance, with increases in plasma insulin; however, women with diabetes mellitus who use progestin-only.sequelae of diabetes mellitus are not fully known, patients receiving such drugs must be closely observed for both short- and long-term complications. Periodic assessment of cardiovascular, ophthalmic, renal and hepatic status is advisable. GLICLAZIDE MR use is not recommended with medications containing alcohol.renal failure, in patients with diabetes mellitus (type 1 or type 2) and/or moderate to severe renal impairment (GFR 60 ml/min/1.73m2). Therefore, the use of COVERSYL® in combination with aliskiren-containing drugs is contraindicated in these patients (see CONTRAINDICATIONS).with responsive, stable, mild, non-ketosis prone, type 2 diabetes mellitus as an adjunct to proper dietary management, exercise, and weight reduction, or when insulin therapy is not appropriate. GLUCOPHAGE can be used as monotherapy or in combination with other antidiabetic agents.Apr 3, 2019 with type 2 diabetes mellitus (T2DM) treated with FORXIGA (dapagliflozin) and other sodium-glucose co-transporter 2 (SGLT2) inhibitors.Not indicated for type 1 diabetes mellitus or treatment of diabetic ketoacidosis. 1. Jardiance Dosage and Administration General. Correct volume depletion prior to initiating empagliflozin; assess renal function prior to treatment and periodically thereafter. 1. Administration Oral Administration. Administer once daily in the morning.Patients with diabetes mellitus (type 1 or type 2) or moderate to severe renal impairment (GFR 60 mL/min/1.73 m2) who are taking ARBs or ACE inhibitors (see WARNINGS AND PRECAUTIONS, Cardiovascular, Dual Blockade of the Renin-Angiotensin System (RAS) and Renal, and DRUG INTERACTIONS, Drug-Drug Interactions, Dual Blockade.
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• Combination with aliskiren-containing drugs in patients with diabetes mellitus (type 1 or type 2) and/or moderate to severe renal impairment (GFR 60 ml/min/1.73m2) [see WARNINGS and PRECAUTIONS, Dual Blockade of the Renin-Angiotensin System (RAS) and Renal, and DRUG INTERACTIONS, Dual Blockade of the Renin-Angiotensin System (RAS)].diabetes mellitus, untreated hyperglycemic events eventually lead to diabetic ketoacidosis, which can cause death. Changes in insulin, manufacturer, type, or method of administration may affect glycemic control and predispose to hyperglycemia. These changes should be made cautiously and only under.However, by the age of seven, an estimated 40% of these companion animals in the United States are either overweight or obese. This excess weight is linked to the onset of diabetes mellitus (DM), a metabolic disease that is most frequently diagnosed in dogs and cats between the ages of seven and nine 1-4. DM is associated with the development.Dec 23, 2016 patients with type 2 diabetes whose hyperglycemia cannot be controlled by Composition and Packaging section of the product monograph.Combination with aliskiren-containing drugs in patients with diabetes mellitus (type 1 or type 2) and/or moderate to severe renal impairment (GFR 60 ml/min/1.73 m2) (see WARNINGS and PRECAUTIONS, Dual Blockade of the Renin-Angiotensin System (RAS) and Renal, and DRUG INTERACTIONS, Dual Blockade of the Renin-Angiotensin System (RAS).In the Western literature pancreatic diabetes is believed to account for only 0.5-1.2% of all patients with diabetes mellitus [50, 51], and in Japan 1.69% of 17,500 diabetic patients.Patients with type 2 diabetes: When deciding about the use of glucagon for the patient with type 2 diabetes, consider those with a long duration of diabetes and/or insulin treatment. Those with advanced type 2 diabetes have a similar decline in counter-regulatory hormones as do those with type 1 diabetes.ezetimibe, alcohol abuse, excessive physical exercise, diabetes with hepatic fatty change situations where an increase in plasma levels of active ingredient may occur). For information on a specific HMG-CoA reductase inhibitor, consult a respective Product Monograph.




Monographie Diabetes mellitus:

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